Evaluation of the efficacy and safety of a novel short stem total hip replacement in dogs with hip osteoarthritis secondary to hip dysplasia

**Enrollment on Hold**

The University of Florida, College of Veterinary Medicine is currently recruiting dogs with hip dysplasia that would benefit from a total hip replacement.

Background: 

A new hip replacement has been developed for dogs. Hip replacement involves replacing the hip joint with synthetic implants. Because less bone is removed with the new hip replacement, there are several possible advantages of this system over current implants, including lower risk of bone fracture. Because this new implant has not yet been used in actual patients, we would like to determine the success rates and complications of the procedure.

Inclusion Criteria:

Your dog may be a candidate for this clinical trial if he/she is:

– 1-8 years of age

– 25-40 kg (55-88 lb)

– Not overweight

– Systemically healthy

– Has no other major active orthopedic problem; for example, elbow dysplasia, patellar luxations, torn cruciate ligaments, angular deformities

– Currently showing symptoms; for example, limping, difficulty rising and exercise intolerance

– Limping on one hind limb more than the other (for example not a symmetric hind limb lameness)

– Has radiographs showing hip dysplasia

Additionally, out of pocket costs are approximately $3500, and your dog must be able to return for rechecks at 3 months, 6 months, and 1 year after surgery

Procedures/Treatment: Your dog will undergo hip replacement with the new implants under anesthesia. At each visit, you will be asked to fill out a questionnaire in order to quantify the progress of your animal. We will perform a detailed examination of your dog, including force platform gait analysis, which measures the amount of weight that is being placed on the legs during trotting. Radiographs will also be performed. Rechecks will be done at 3 months, 6 months, 12 months, 2 years, and 5 years after surgery.

Cost: The study will cover all costs related to the implant. You will be responsible for the cost of initial evaluation and the other surgery fees. Out-of-pocket costs will be approximately $3500 (normal hip replacement is ~$6000). Should your animal develop implant failure or aseptic loosening (loosening not caused by infection), up to $4000 of medical care will be covered to address these complications. You will receive $100 for each visit at 1 year, 2 years, and 5 years after surgery. All radiographs (including sedation) and examination fees at 6 months and beyond will be paid by the study. That is, you will need to pay for the radiographs and exam before surgery and at 3 months, but not after that.

Study Contact: If you would like to be considered for the study, please call the UF Small Animal Hospital to schedule an appointment with the Surgery Service at (352) 392-2235. For other questions regarding the study, please complete the Study Interest Form.